Translating Mechanisms Orofacial Neurological D... May 2026

: Research into the transition from acute to chronic pain, driven by peripheral and central sensitization . This includes studying "maladaptive plasticity" within the trigeminal system, where persistent signals lead to chronic conditions like temporomandibular disorders (TMD) .

: A growing focus on how non-neuronal cells—such as satellite glial cells and macrophages in the trigeminal ganglion—regulate neuronal excitability and contribute to neuropathic pain. Translating Mechanisms Orofacial Neurological D...

: Utilizing advanced techniques like single-cell transcriptomics and in vivo imaging to identify novel molecular targets, including ion channels and metabolic regulators, for more precise therapies. Translational Strategies : Research into the transition from acute to

The field focuses on several critical neurological and physiological mechanisms: including ion channels and metabolic regulators

The goal of this research is to turn laboratory discoveries into better patient care through: Translating Mechanisms of Orofacial Neurological Disorder