Seeing Sheldon actually stand up to his favorite person in the world to defend Amy shows just how much their relationship has evolved.

In "The Physical Impossibility of Death in the Mind of Someone Living," the legendary Me-Maw (played by June Squibb) finally arrives in Pasadena, and she isn't exactly Amy’s biggest fan.

The episode title is a reference to a famous 1991 artwork by Damien Hirst—a tiger shark preserved in formaldehyde. It’s a classic Big Bang nod to high-concept art and science!

It takes some courage, but Amy finally tells Me-Maw that she loves Sheldon just as much as she does.

Me-Maw is fiercely protective of her "Moonpie" and makes it clear she hasn't forgotten Amy breaking Sheldon’s heart during their breakup.

This episode of The Big Bang Theory explores the chaos that ensues when Sheldon’s "Me-Maw" comes to visit and clashes with Amy.

[s2e16] The Physical Impossibility Of Death In ... May 2026

Seeing Sheldon actually stand up to his favorite person in the world to defend Amy shows just how much their relationship has evolved.

In "The Physical Impossibility of Death in the Mind of Someone Living," the legendary Me-Maw (played by June Squibb) finally arrives in Pasadena, and she isn't exactly Amy’s biggest fan. [S2E16] The Physical Impossibility of Death in ...

The episode title is a reference to a famous 1991 artwork by Damien Hirst—a tiger shark preserved in formaldehyde. It’s a classic Big Bang nod to high-concept art and science! Seeing Sheldon actually stand up to his favorite

It takes some courage, but Amy finally tells Me-Maw that she loves Sheldon just as much as she does. It’s a classic Big Bang nod to high-concept

Me-Maw is fiercely protective of her "Moonpie" and makes it clear she hasn't forgotten Amy breaking Sheldon’s heart during their breakup.

This episode of The Big Bang Theory explores the chaos that ensues when Sheldon’s "Me-Maw" comes to visit and clashes with Amy.