In anime production, layers are labeled alphabetically (e.g., Layer A for the character's body, Layer B for moving hair/tentacles) to separate static and moving parts.
Use procedural motor systems to automate the "wavy" idle animation of long tentacle chains. 3. Anime-Specific Animation Techniques
To achieve a professional "anime" look, apply these stylistic principles: How I Animate a Scene from Beginning to End
For more direct control, use Inverse Kinematics (IK) to drive the entire tentacle chain with a single target controller. 2D Workflow (After Effects)