: When thrombolysis is contraindicated or fails, options include catheter-directed thrombectomy or surgical embolectomy. Prognosis and Follow-Up
Acute Pulmonary Embolism (PE) is a critical cardiovascular emergency characterized by the sudden obstruction of a pulmonary artery, typically by a blood clot originating from deep vein thrombosis (DVT) in the lower limbs. As a leading cause of in-hospital mortality, its management requires rapid risk stratification and adherence to standardized clinical guidelines. Pathophysiology and Etiology Download Embolie pulmonaire aiguГ« pdf
: For high-risk (hemodynamically unstable) patients, systemic thrombolysis (e.g., Alteplase) is recommended to rapidly dissolve the clot. : When thrombolysis is contraindicated or fails, options
: Roughly 70% to 80% of emboli arise from proximal deep veins in the legs or pelvis. systemic thrombolysis (e.g.
: Once a clot lodges in the pulmonary vascular bed, it increases pulmonary vascular resistance, which can lead to acute right ventricular (RV) failure and hemodynamic collapse.