logo

Dг¶n. Gг¶khan Tгјrkmen Oдџuz Yerli. Ud. May 2026

Software for motif discovery and next generation sequencing analysis



HOMER (Hypergeometric Optimization of Motif EnRichment) is a suite of tools for Motif Discovery and ChIP-Seq analysis. It is a collection of command line programs for unix-style operating systems written in mostly perl and c++. Homer was primarily written as a de novo motif discovery algorithm that is well suited for finding 8-12 bp motifs in large scale genomics data.

Hardware Requirements (recommended): 2+ Gb memory (4-8+ Gb), 10+ Gb Hard Drive space (50+ Gb)
Software Requirements: Unix compatible OS (or cygwin), perl, gcc, make, wget (optional for full functionality: R, DESeq2, blat, bedGraphToBigWig, liftOver)
License: GPLv3

HOMER works on pretty much any Linux/UNIX systems, including MacOS (if Xcode compilers are installed) and on Windows using either cygwin or a Linux subsystem.

If you are looking specifically for HOMER2, you are in the right place! HOMER2 is integrated into HOMER.

Full Program Download

Dг¶n. Gг¶khan Tгјrkmen Oдџuz Yerli. Ud. May 2026

Nearly two decades since its release, "Dön" remains a staple in playlists for those seeking "timeless discoveries".

Even after 17+ years, the song is hailed as a "classic" that listeners still find new details in with every play. Community Perspective Fans often describe the track as a visceral experience: DГ¶n. GГ¶khan TГјrkmen OДџuz Yerli. Ud.

“This song has a very deep meaning... the cry of someone who can't forget his ex-lover. No place in Istanbul helped me forget you.” YouTube · BeansX21 Reactions Sen İstanbul'sun (Tuana) (Live on The Voice Kids Germany) Nearly two decades since its release, "Dön" remains

The song a standout track from Gökhan Türkmen's debut album Büyük İnsan , is a timeless piece of Turkish pop-ballad history that continues to resonate with "Gökhan Türkmen gourmets" for its emotional depth and melodic richness. The Soul of the Song the cry of someone who can't forget his ex-lover

The inclusion of the Ud , masterfully played by Oğuz Yerli (Hasan Oğuz Yerli), adds a traditional and melancholic layer that elevates the song beyond standard pop.

Program Components and Older Versions

homer2 program - key executable for HOMER motif discovery (homerCppOnly.*.zip). (This archive actually contains all of the c++ executable, not just homer2).  Unzip in the desired directory and simply type "make" to compile the program.

The configuration script really doesn't deal with older versions, but you can download older versions yourself should you really feel like using inferior data or software!
Old Versions of HOMER Software
Old Versions of Organism Packages
Old Versions of Promoter Packages
Old Versions of Genome Packages

Update Information

Change Log - Short description of recent changes

update.txt - Current HOMER configuration list (Currently support human hg17/hg18/hg19, mouse mm8/mm9, rat rn4, X. tropicalis xenTro2, drosophila dm3, and C. elegans ce6, Zebrafish danRer7, yeast sacCer2, Arabidopsis tair10, Rice msu6, Pombe ASM294v1)


DГ¶n. GГ¶khan TГјrkmen OДџuz Yerli. Ud.
Can't figure something out? Questions, comments, concerns, or other feedback:
cbenner@ucsd.edu