: Fluconazole , itraconazole , and voriconazole . 2. Polyenes
: Polyene drugs act directly on the fungal cell membrane by binding to ergosterol. antifungal agent
: Allylamines inhibit the enzyme squalene epoxidase. : Fluconazole , itraconazole , and voriconazole
: This class targets the fungal cell wall rather than the membrane. They inhibit the enzyme -(1,3)-D-glucan synthase. Effect : This blocks the synthesis of antifungal agent
