Abnormal Serum Light Chain Ratio May 2026

Conditions like multiple myeloma or MGUS (Monoclonal Gammopathy of Undetermined Significance) can cause one type of light chain to be overproduced, skewing the ratio.

While an abnormal ratio can sometimes indicate a serious condition, it is often caused by non-cancerous factors. Common Causes of an Abnormal Ratio Abnormal Serum Light Chain Ratio

A rare condition where misfolded light chains build up in organs like the heart or kidneys. Typical Next Steps Abnormal Serum Light Chain Ratio

Your doctor will likely look at your results alongside other health markers to determine if follow-up is needed: Free Light Chains: MedlinePlus Medical Test Abnormal Serum Light Chain Ratio